References for Heart Disease and Stem Cell Therapy

Liu L, Marti G, Wei X, Zhang X, Zhang H, Liu Y, Nastai M, Semenza GL, Harmon J. Age-dependent impairment of HIF-1α expression in diabetic mice: correction with electroporation-facilitated gene therapy increases wound healing, angiogenesis, and circulating angiogenic cells. J. Cell. Physiol. 217:319-27 (2008).

Sarkar K, Fox-Talbot K, Steenbergen C, Bosch-Marcé M, Semenza GL. Adenoviral transfer of HIF-1α enhances vascular responses to critical limb ischemia in diabetic mice. Proc. Natl. Acad. Sci. USA 106:18769-18774 (2009).

Rey S, Lee K, Wang CJ, Gupta K, Chen S, McMillan A, Bhise N, Levchenko A, Semenza GL. Synergistic effect of HIF-1α gene therapy and HIF-1-activated bone marrow-derived angiogenic cells in a mouse model of limb ischemia. Proc. Natl. Acad. Sci. USA 106:20399-20404 (2009).

Rey S, Semenza GL. Hypoxia-inducible factor 1-dependent mechanisms of vascularization and vascular remodeling. Cardiovasc. Res. 86:236-242 (2010).

Hirsch, A.T., Critical Limb Ischemia and Stem Cell Research, Anchoring Hope With Informed Adverse Event Reporting, Circulation. 2006;114:2581-2583.

Jialal I, Devaraj S, Singh U, Huet BA., Decreased number and impaired functionality of endothelial progenitor cells in subjects with metabolic syndrome: implications for increased cardiovascular risk. Atherosclerosis. 2010 Jul;211(1):297-302. Epub 2010 Feb 4.

Fadini GP, Maruyama S, Ozaki T, Taguchi A, Meigs J, Dimmeler S, Zeiher AM, de Kreutzenberg S, Avogaro A, Nickenig G,Schmidt-Lucke C, Werner N., Circulating progenitor cell count for cardiovascular risk stratification: a pooled analysis, PLoS One. 2010 Jul 9;5(7):e11488.

Buja LM, Vela D., Immunologic and inflammatory reactions to exogenous stem cells implications for experimental studies and clinical trials for myocardial repair, J Am Coll Cardiol. 2010 Nov 16;56(21):1693-700.

X.F. Yang, Immunology of stem cells and cancerstem cells, Cell Mol Immunol 4 (2007), pp. 161–171.

T. Kofidis, J.L. deBruin and M. Tanaka et al., They are not stealthy in the heart: embryonic stem cells trigger cell infiltration, humoral and T-lymphocyte-based host immune response, Eur J Cardiothorac Surg 28 (2005), pp. 461–466.

A.J. Poncelet, J. Vercruysse, A. Saliez and P. Gianello, Although pig allogeneic mesenchymal stem cells are not immunogenic in vitro, intracardiac injection elicits an immune response in vivo, Transplantation 83 (2007), pp. 783–790.

T. Yasuda, R.D. Weisel, C. Kiani, D.A. Mickle, M. Maganti and R.K. Li, Quantitative analysis of survival of transplanted smooth muscle cells with real-time polymerase chain reaction, J Thorac Cardiovasc Surg 129 (2005), pp. 904–911.

Dinsmore JH, Dib N., Stem cells and cardiac repair: a critical analysis, J Cardiovasc Transl Res. 2008 Mar;1(1):41-54. Epub 2008 Jan 31.

Szekanecz Z, Besenyei T, Szentpétery A, Koch AE., Angiogenesis and vasculogenesis in rheumatoid arthritis, Curr Opin Rheumatol. 2010 May;22(3):299-306.

Weber AJ, De Bandt M., Angiogenesis: general mechanisms and implications for rheumatoid arthritis, Joint Bone Spine. 2000;67(5):366-83.

Olin JW. Thromboangiitis obliterans (Buerger’s disease). N Engl J Med. 2000; 343: 864–869.

Dzau VJ, Gnecchi M, Pachori AS, Morello F, and Melo LG. Therapeutic potential of endothelial progenitor cells in cardiovascular diseases. Hypertension.2005; 46: 7–18.

Asahara T, Masuda H, Takahashi T, Kalka C, Pastore C, Silver M, Kearne M, Magner M, Isner JM. Bone marrow origin of endothelial progenitor cells responsible for postnatal vasculogenesis in physiological and pathological neovascularization. Circ Res. 1999; 85: 221–228.

Miyamoto K, Nishigami K, Nagaya N, Akutsu K, Chiku M, Kamei M, Soma T, Miyata S, Higashi M, Tanaka R, Nakatani T, Nonogi H, Takeshita S. Unblinded pilot study of autologous transplantation of bone marrow mononuclear cells in patients with thromboangiitis obliterans. Circulation. 2006; 114: 2679–2684

Huang, P., Shangzhu, L., et al, Autologous Transplantation of Granulocyte Colony–Stimulating Factor–Mobilized Peripheral Blood Mononuclear Cells Improves Critical Limb Ischemia in Diabetes, Diabetes Care September 2005 vol. 28 no. 9 2155-2160